proteinfolding相关论文
Unfolded protein response(UPR)is a stress response that is specific to the endoplasmic re-ticulum(ER).UPR is activated u......
Protein Folding and Protein-Protein Interaction Analysis Using Homo- and Hetero-bifunctional Cross-l
Chemical cross-linking combined with mass spectrometry (CXMS) is a powerful tool for protein folding and protein-protein......
Understanding the folding and stability of a designed WW domain protein with replica exchange molecu
Background: Understanding the folding mechanism of the β-sheet structure is crucial for a general and comprehensive und......
Molecular Dynamic Simulations of the Trp-cage Folding/unfolding Mechanism and its Folding-related Pr
The major driving force of protein folding depends on their inter-residue interactions,especially for sidechain-sidechai......
Tightening up the structure,lighting up the pathway:Application of molecular constraints and light t
Chemical cross-linking provides an effective avenue to reduce the conformational entropy of polypeptide chains and hence......
Subdomain specific collapse of denatured states of staphylococcal nuclease revealed by single molecu
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Glutathione transferases (GSTs) are an important class of enzymes involved in cellular detoxification.GSTs are found in ......
Cystic fibrosis(CF),one of the most common inherited disease in the Caucasian population,is caused by mutations of the C......
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Maintaining proteostasis is an essential housekeeping function for cell survival.It involves chaperones and degradative ......
Understanding the folding and stability of a designed WW domain protein with replica exchange molecu
WW domain proteins are usually regarded as simple models for understanding the folding mechanisrn of β-sheet.CC45 is an......
The study of protein folding is fundamental and important in the multidisciplinary field because a diversity of diseases......
Molecular Dynamic Characterization of Identifying the Intermediates during the Foldingunfolding of P
Protein folding/unfolding has long represented one of the considerable challenges.In this work,a total of 4.0-μs ex......
Due to the limitation on the calculating power of the computer, it is very difficult to simulate the whole folding p......
热力学的假设和运动稳定性当前被用来理解蛋白质合拢。前者假设那免费精力最小是在大多数情况中的独占的主导的机制，当一些蛋白质举......
The fundamental law for protein folding is the thermodynamic principle.The amino acid sequence of a protein determines i......
遗传算法是一种模仿自然进化进程的新颖的启发式优化方法。通过它，人们可以在计算机上对所需的各种问题实施进化操作，最终产生理想的......
